No

Topics

Methods

Media

Time

Allotted

(Hrs)

Total

(Hrs)

1.

Introduction to Biochemistry

Basic principles of Biochemistry, Importance of Biochemistry in relation to other biomedical sciences.

Lecture

LCD

1/2

1/2

2.

Enzymology

Definition, Distribution, Nature, Nomenclature, Classification, Specificity, Mechanism of action,

Coenzymes and isoenzymes,

Factors affecting the velocity of an

enzyme-catalyzed reaction.

Importance of enzymes in clinical

medicine.

Lecture

Tutorial

Practical

white board

LCD

Lab.

8

2

3

13

3.

Chemistry of Blood

Functions of blood, General features of blood, Haemoglobin (Hb) structure, normal forms of Hb, Synthesis & breakdown of

haemoglobin (metabolism of

bilirubin), Importance of bilirubin

metabolism, Functions of

haemoglobin, Heamoglobin variants & their prevalence in Myanmar.

Plasma protein types, methods of separation, Synthesis and functions of plasma proteins, normal plasma protein concentrations, Factors influencing plasma protein concentration. Immunoglobulins.

Lecture

Tutorial

Practical

white board

LCD

Lab:

8

2

2

12

4.

Chemistry of Respiration

Transport of respiratory gases:

oxygen & carbon dioxide, Factors

influencing oxygen haemoglobin

dissociation & their biomedical

importance

Lecture

Tutorial

White board

LCD

4 1/2

1

5 1/2

5.

Food & Nutrition

Definitions in nutrition, dietary requirement, energy content of food, types and functions of  carbo –hydrates, types and functions of lipids, types of amino acids, quality of proteins and functions,

Balanced diet & its components.

Planning a balanced diet.

Sources, daily requirements,

biochemical functions, deficiency

and excess state of  vitamins,

Minerals, and water, body mass index

Lecture

Tutorial

Practical

White board

LCD

Lab

16

4

1

21

No.

Topics

Methods

Media

Time

Allotted

(Hrs)

Total

(Hrs)

6.

Molecular Biology

Chromosome, types of nucleic acids, structure of nucleic acids, Gene, genetic code & gene expression. Functions of DNA and RNA. Protein synthesis in prokaryotes & Eukaryotes, Biomedical aspects of genetics mutations, Importance of recombinant DNA technology & PCR

Lecture

Tutorial

White board

LCD

12

2

14

7.

Digestion & Absorption of

Nutrients, Liver & Bile

Digestion and absorption of

carbohydrate, lipid & protein.

Functions of the liver and bile

Lecture

Tutorial

Practical

White board

LCD

Lab.

8

2

2

12

8.

Bioenergetics, Biologic Oxidation

& Energy Metabolism

The role of ATP & other energy rich

compounds, Respiratory & their

biomedical importance. Energy

balance. Metabolic rate, basal

metabolic rate & factors influencing

MR & BMR.

Lecture

Tutorial

White board

LCD

8

2

10

9.

Intermediary Metabolism

Fate of dietary carbohydrates & their

biomedical importance. Blood

glucose level & factors controlling

the blood glucose concentration.

Metabolism of fatty acids & its

biomedical importance.

Metabolism of ketone bodies & its

biomedical importance.

Metabolism of phospholipids & its

biomedical importance

Metabolism of cholesterol, blood

cholesterol & its clinical importance

Plasma lipoproteins

Metabolism of adipose tissue.

Fate of dietary proteins &

nucleoproteins.

Metabolism of ammonia, blood

ammonia and its clinical

significance. Synthesis and

Catabolic fate of purine &

pyrimidine base.

Blood uric acid and its clinical

importance.

Lecture

Tutorial

Practical

White board

LCD

Lab

27

4

3

34

10.

Chemistry of Hormones &

Calcium Metabolism

General characteristics of hormones,

Mechanism of action of hormones.

Biosynthesis of thyroid hormones,

protein hormones & steroid

hormones (including sex hormones)

and their biomedical importance

Lecture

Tutorial

Practical

White board

LCD

Lab.

8

1

1

10

11.

Body fluids & Electrolytes

Body fluid compartments:

distribution & composition. Plasma

electrolytes. Water balance.

Lecture

Tutorial

Practical

White board

LCD

Lab.

4

1

1

6

12.

Acid Base Balance

Blood pH: sources of hydrogen ions

& sources of alkali, normal pH,

Maintenance of normal blood pH:

importance of blood buffers, tissue

buffers; role of the respiratory

system and the kidney in

maintaining the normal blood pH.

Acid-base imbalances.

Lecture

Tutorial

White board LCD

4

1

5

13.

Revision

Theory

Practical

White board

LCD

Lab.

8

4

12

LECTURE

108

TUTORIAL

22

PRACTICAL

13

REVISION

12

TOTAL TEACHING HOURS

155